We are the Protein Evolution group based at BioQuant and the Biochemie Zentrum (BZH) at the University of Heidelberg in the Faculties of Engineering Sciences and Life Sciences. We are interested in all aspects of protein structure, function and evolution. We mostly focus on studies of molecular interactions: protein-protein, protein-peptide, protein-chemical, etc. For the last decade our focus has been almost exclusiely on how genetic variants or post-translational modifications affect biomolecular interactions and structure, with many clinical applications and studies. For more information click on Research above. If you wish to run some of our online tools, please click on Services above.